Human Immunodeficiency Virus Protease Inhibitors Interact with ATP Binding Cassette Transporter 4/Multidrug Resistance Protein 4: A Basis for Unanticipated Enhanced Cytotoxicity

Human immunodeficiency virus (HIV) pharmacotherapy, by combining different drug classes such as nucleoside analogs and HIV protease inhibitors (PIs), has increased HIV-patient life expectancy. Consequently, among these patients, an increase in non-HIV–associated cancers has produced a patient cohort...

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Main Authors: Fukuda, Yu, Takenaka, Kazumasa, Sparreboom, Alex, Cheepala, Satish B., Wu, Chung-Pu, Ekins, Sean, Ambudkar, Suresh V., Schuetz, John D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The American Society for Pharmacology and Experimental Therapeutics 2013
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Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876819/
https://ncbi.nlm.nih.gov/pubmed/23775562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.086967
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