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A Generic Coalescent-based Framework for the Selection of a Reference Panel for Imputation

An important component in the analysis of genome-wide association studies involves the imputation of genotypes that have not been measured directly in the studied samples. The imputation procedure uses the linkage disequilibrium (LD) structure in the population to infer the genotype of an unobserved...

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Detalhes bibliográficos
Main Authors: Paşaniuc, Bogdan, Avinery, Ram, Gur, Tom, Skibola, Christine F., Bracci, Paige M., Halperin, Eran
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876740/
https://ncbi.nlm.nih.gov/pubmed/21058333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20505
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