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A Generic Coalescent-based Framework for the Selection of a Reference Panel for Imputation

An important component in the analysis of genome-wide association studies involves the imputation of genotypes that have not been measured directly in the studied samples. The imputation procedure uses the linkage disequilibrium (LD) structure in the population to infer the genotype of an unobserved...

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Bibliografiska uppgifter
Huvudupphovsmän: Paşaniuc, Bogdan, Avinery, Ram, Gur, Tom, Skibola, Christine F., Bracci, Paige M., Halperin, Eran
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876740/
https://ncbi.nlm.nih.gov/pubmed/21058333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20505
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