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Genotype Imputation Reference Panel Selection Using Maximal Phylogenetic Diversity

The recent dramatic cost reduction of next-generation sequencing technology enables investigators to assess most variants in the human genome to identify risk variants for complex diseases. However, sequencing large samples remains very expensive. For a study sample with existing genotype data, such...

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Detalhes bibliográficos
Main Authors: Zhang, Peng, Zhan, Xiaowei, Rosenberg, Noah A., Zöllner, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781962/
https://ncbi.nlm.nih.gov/pubmed/23934887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.154591
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