Rapid genotype imputation from sequence with reference panels

Inexpensive genotyping methods are essential to modern genomics. Here we present QUILT, which performs diploid genotype imputation using low-coverage whole genome sequence data. QUILT employs Gibbs sampling to partition reads into maternal and paternal sets, facilitating rapid haploid imputation usi...

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Vydáno v:Nat Genet
Hlavní autoři: Davies, Robert W, Kucka, Marek, Su, Dingwen, Shi, Sinan, Flanagan, Maeve, Cunniff, Christopher M, Chan, Yingguang Frank, Myers, Simon
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611184/
https://ncbi.nlm.nih.gov/pubmed/34083788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-021-00877-0
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