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Rapid genotype imputation from sequence with reference panels
Inexpensive genotyping methods are essential to modern genomics. Here we present QUILT, which performs diploid genotype imputation using low-coverage whole genome sequence data. QUILT employs Gibbs sampling to partition reads into maternal and paternal sets, facilitating rapid haploid imputation usi...
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| Publicat a: | Nat Genet |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7611184/ https://ncbi.nlm.nih.gov/pubmed/34083788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-021-00877-0 |
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