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A Generic Coalescent-based Framework for the Selection of a Reference Panel for Imputation

An important component in the analysis of genome-wide association studies involves the imputation of genotypes that have not been measured directly in the studied samples. The imputation procedure uses the linkage disequilibrium (LD) structure in the population to infer the genotype of an unobserved...

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Hlavní autoři: Paşaniuc, Bogdan, Avinery, Ram, Gur, Tom, Skibola, Christine F., Bracci, Paige M., Halperin, Eran
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876740/
https://ncbi.nlm.nih.gov/pubmed/21058333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20505
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