Scrapie Protein Degradation by Cysteine Proteases in CD11c(+) Dendritic Cells and GT1-1 Neuronal Cells

Dendritic cells (DC) of the CD11c(+) myeloid phenotype have been implicated in the spread of scrapie in the host. Previously, we have shown that CD11c(+) DC can cause a rapid degradation of proteinase K-resistant prion proteins (PrP(Sc)) in vitro, indicating a possible role of these cells in the cle...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Luhr, Katarina M., Nordström, Elin K., Löw, Peter, Ljunggren, Hans-Gustaf, Taraboulos, Albert, Kristensson, Krister
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2004
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387668/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15078959/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.9.4776-4782.2004
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