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Scrapie Protein Degradation by Cysteine Proteases in CD11c(+) Dendritic Cells and GT1-1 Neuronal Cells
Dendritic cells (DC) of the CD11c(+) myeloid phenotype have been implicated in the spread of scrapie in the host. Previously, we have shown that CD11c(+) DC can cause a rapid degradation of proteinase K-resistant prion proteins (PrP(Sc)) in vitro, indicating a possible role of these cells in the cle...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2004
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC387668/ https://ncbi.nlm.nih.gov/pubmed/15078959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.9.4776-4782.2004 |
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