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Scrapie Protein Degradation by Cysteine Proteases in CD11c(+) Dendritic Cells and GT1-1 Neuronal Cells

Dendritic cells (DC) of the CD11c(+) myeloid phenotype have been implicated in the spread of scrapie in the host. Previously, we have shown that CD11c(+) DC can cause a rapid degradation of proteinase K-resistant prion proteins (PrP(Sc)) in vitro, indicating a possible role of these cells in the cle...

詳細記述

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書誌詳細
主要な著者: Luhr, Katarina M., Nordström, Elin K., Löw, Peter, Ljunggren, Hans-Gustaf, Taraboulos, Albert, Kristensson, Krister
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC387668/
https://ncbi.nlm.nih.gov/pubmed/15078959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.9.4776-4782.2004
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