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Use of glass transitions in carbohydrate excipient design for lyophilized protein formulations
This work describes an effort to apply methods from process systems engineering to a pharmaceutical product design problem, with a novel application of statistical approaches to comparing solutions. A computational molecular design framework was employed to design carbohydrate molecules with high gl...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3876287/ https://ncbi.nlm.nih.gov/pubmed/24385675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.compchemeng.2011.07.018 |
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