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1,25-Dihydroxyvitamin D(3) selectively and reversibly impairs T helper-cell CNS localization
Pharmacologic targeting of T helper (T(H)) cell trafficking poses an attractive opportunity for amelioration of autoimmune diseases such as multiple sclerosis (MS). MS risk is associated with vitamin D deficiency, and its bioactive form, 1,25-dihydroxyvitamin D3 [1,25(OH)(2)D(3)], has been shown to...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3876241/ https://ncbi.nlm.nih.gov/pubmed/24324134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1306072110 |
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