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Whole chromosome gain does not in itself confer cancer-like chromosomal instability
Constitutional aneuploidy is typically caused by a single-event meiotic or early mitotic error. In contrast, somatic aneuploidy, found mainly in neoplastic tissue, is attributed to continuous chromosomal instability. More debated as a cause of aneuploidy is aneuploidy itself; that is, whether aneupl...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3876223/ https://ncbi.nlm.nih.gov/pubmed/24324169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311163110 |
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