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Whole Chromosome Instability induces senescence and promotes SASP

Age-related accumulation of ploidy changes is associated with decreased expression of genes controlling chromosome segregation and cohesin functions. To determine the consequences of whole chromosome instability (W-CIN) we down-regulated the spindle assembly checkpoint component BUB1 and the mitotic...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Andriani, Grasiella Angelina, Almeida, Vinnycius Pereira, Faggioli, Francesca, Mauro, Maurizio, Tsai, Wanxia Li, Santambrogio, Laura, Maslov, Alexander, Gadina, Massimo, Campisi, Judith, Vijg, Jan, Montagna, Cristina
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059742/
https://ncbi.nlm.nih.gov/pubmed/27731420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35218
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