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Rare event of histone demethylation can initiate singular gene expression of olfactory receptors

Mammals sense odors through the gene family of olfactory receptors (ORs). Despite the enormous number of OR genes (∼1,400 in mouse), each olfactory sensory neuron expresses one, and only one, of them. In neurobiology, it remains a long-standing mystery how this singularity can be achieved despite in...

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Autors principals: Tan, Longzhi, Zong, Chenghang, Xie, X. Sunney
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876194/
https://ncbi.nlm.nih.gov/pubmed/24344257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1321511111
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