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Rare event of histone demethylation can initiate singular gene expression of olfactory receptors

Mammals sense odors through the gene family of olfactory receptors (ORs). Despite the enormous number of OR genes (∼1,400 in mouse), each olfactory sensory neuron expresses one, and only one, of them. In neurobiology, it remains a long-standing mystery how this singularity can be achieved despite in...

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書目詳細資料
Main Authors: Tan, Longzhi, Zong, Chenghang, Xie, X. Sunney
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876194/
https://ncbi.nlm.nih.gov/pubmed/24344257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1321511111
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