Measuring dopaminergic function in the 6-OHDA-lesioned rat: a comparison of PET and microdialysis

BACKGROUND: [(18) F]fluorodopa (FDOPA) positron emission tomography (PET) allows assessment of levodopa (LDOPA) metabolism and is widely used to study Parkinson's disease. We examined how [(18) F]FDOPA PET-derived kinetic parameters relate the dopamine (DA) and DA metabolite content of extracel...

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Bibliografiske detaljer
Main Authors: Walker, Matthew D, Dinelle, Katherine, Kornelsen, Rick, Lee, Anna, Farrer, Matthew J, Stoessl, A Jon, Sossi, Vesna
Format: Artigo
Sprog:Inglês
Udgivet: Springer 2013
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875899/
https://ncbi.nlm.nih.gov/pubmed/24088510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2191-219X-3-69
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