Use of [(18)F]FDOPA-PET for in vivo evaluation of dopaminergic dysfunction in unilaterally 6-OHDA-lesioned rats

BACKGROUND: We evaluated the utility of L-3,4-dihydroxy-6-[(18)F]fluoro-phenylalanine ([(18)F]FDOPA) positron emission tomography (PET) as a method for assessing the severity of dopaminergic dysfunction in unilaterally 6-hydroxydopamine (6-OHDA)-lesioned rats by comparing it with quantitative bioche...

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Detalhes bibliográficos
Main Authors: Kyono, Kiyoshi, Takashima, Tadayuki, Katayama, Yumiko, Kawasaki, Toshiyuki, Zochi, Riyo, Gouda, Maki, Kuwahara, Yasuhiro, Takahashi, Kazuhiro, Wada, Yasuhiro, Onoe, Hirotaka, Watanabe, Yasuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Springer 2011
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251329/
https://ncbi.nlm.nih.gov/pubmed/22214344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2191-219X-1-25
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