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The Parkinsonian mimetic, 6-OHDA, impairs axonal transport in dopaminergic axons

6-hydroxydopamine (6-OHDA) is one of the most commonly used toxins for modeling degeneration of dopaminergic (DA) neurons in Parkinson's disease. 6-OHDA also causes axonal degeneration, a process that appears to precede the death of DA neurons. To understand the processes involved in 6-OHDA-med...

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Detalhes bibliográficos
Main Authors: Lu, Xi, Kim-Han, Jeong Sook, Harmon, Steve, Sakiyama-Elbert, Shelly E, O'Malley, Karen L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016665/
https://ncbi.nlm.nih.gov/pubmed/24885281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-9-17
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