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κ-Opioid Tolerance and Dependence in Cultures of Dopaminergic Midbrain Neurons
Repeated cocaine exposure upregulates κ opioids and their receptors in the mesocorticolimbic system; the ensuing κ-mediated dysphoria appears to contribute to addiction and withdrawal. As a potential rehabilitation strategy to reverse cocaine-induced κ sensitization, the present study used tritiated...
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| Publicado no: | J Neurosci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6783098/ https://ncbi.nlm.nih.gov/pubmed/10407016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-14-05750.1999 |
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