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Neuroprotective effects of edaravone-administration on 6-OHDA-treated dopaminergic neurons

BACKGROUND: Parkinson's disease (PD) is a neurological disorder characterized by the degeneration of nigrostriatal dopaminergic systems. Free radicals induced by oxidative stress are involved in the mechanisms of cell death in PD. This study clarifies the neuroprotective effects of edaravone (M...

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Detalhes bibliográficos
Main Authors: Ji Yuan, Wen, Yasuhara, Takao, Shingo, Tetsuro, Muraoka, Kenichiro, Agari, Takashi, Kameda, Masahiro, Uozumi, Takashi, Tajiri, Naoki, Morimoto, Takamasa, Jing, Meng, Baba, Tanefumi, Wang, Feifei, Leung, Hanbai, Matsui, Toshihiro, Miyoshi, Yasuyuki, Date, Isao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533664/
https://ncbi.nlm.nih.gov/pubmed/18671880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-9-75
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