[(11)C]PBR28 PET imaging is sensitive to neuroinflammation in the aged rat

Neuroinflammation in the aging rat brain was investigated using [(11)C]PBR28 microPET (positron emission tomography) imaging. Normal rats were studied alongside LRRK2 p.G2019S transgenic rats; this mutation increases the risk of Parkinson's disease in humans. Seventy [(11)C]PBR28 PET scans were...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Walker, Matthew D, Dinelle, Katherine, Kornelsen, Rick, Lee, Nathan V, Miao, Qing, Adam, Mike, Takhar, Christine, Mak, Edwin, Schulzer, Michael, Farrer, Matthew J, Sossi, Vesna
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528008/
https://ncbi.nlm.nih.gov/pubmed/25833342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2015.54
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