Aberrantly hypermethylated Homeobox A2 derepresses metalloproteinase-9 through TBP and promotes invasion in Nasopharyngeal carcinoma

Nasopharyngeal carcinoma (NPC) is notorious for its high invasiveness and metastatic ability. In this study, we identified a differential hypermethylated transcription repressor, Homeobox A2 (HOXA2), which may render NPC cells invasive and metastatic. Aberrant hypermethylation of HOXA2 led to low RN...

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Detalhes bibliográficos
Main Authors: Li, Hsin-Pai, Peng, Chen-Ching, Chung, I-Che, Huang, Mei-Yuan, Huang, Shao-Tung, Chen, Chia-Chun, Chang, Kai-Ping, Hsu, Cheng-Lung, Chang, Yu-Sun
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2013
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875777/
https://ncbi.nlm.nih.gov/pubmed/24243817
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