Computational methods for detecting copy number variations in cancer genome using next generation sequencing: principles and challenges

Accurate detection of somatic copy number variations (CNVs) is an essential part of cancer genome analysis, and plays an important role in oncotarget identifications. Next generation sequencing (NGS) holds the promise to revolutionize somatic CNV detection. In this review, we provide an overview of...

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Hlavní autoři: Liu, Biao, Morrison, Carl D., Johnson, Candace S., Trump, Donald L., Qin, Maochun, Conroy, Jeffrey C., Wang, Jianmin, Liu, Song
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2013
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875755/
https://ncbi.nlm.nih.gov/pubmed/24240121
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