Copy number variation of individual cattle genomes using next-generation sequencing

Copy number variations (CNVs) affect a wide range of phenotypic traits; however, CNVs in or near segmental duplication regions are often intractable. Using a read depth approach based on next-generation sequencing, we examined genome-wide copy number differences among five taurine (three Angus, one...

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Autores principales: Bickhart, Derek M., Hou, Yali, Schroeder, Steven G., Alkan, Can, Cardone, Maria Francesca, Matukumalli, Lakshmi K., Song, Jiuzhou, Schnabel, Robert D., Ventura, Mario, Taylor, Jeremy F., Garcia, Jose Fernando, Van Tassell, Curtis P., Sonstegard, Tad S., Eichler, Evan E., Liu, George E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317159/
https://ncbi.nlm.nih.gov/pubmed/22300768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.133967.111
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