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The SAS-5 N-terminal domain is a tetramer, with implications for centriole assembly in C. elegans
The centriole is a conserved microtubule-based organelle essential for both centrosome formation and cilium biogenesis. It has a unique 9-fold symmetry and its assembly is governed by at least five component proteins (SPD-2, ZYG-1, SAS-5, SAS-6 and SAS-4), which are recruited in a hierarchical order...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3875647/ https://ncbi.nlm.nih.gov/pubmed/24778935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/worm.25214 |
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