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The SAS-5 N-terminal domain is a tetramer, with implications for centriole assembly in C. elegans

The centriole is a conserved microtubule-based organelle essential for both centrosome formation and cilium biogenesis. It has a unique 9-fold symmetry and its assembly is governed by at least five component proteins (SPD-2, ZYG-1, SAS-5, SAS-6 and SAS-4), which are recruited in a hierarchical order...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shimanovskaya, Ekaterina, Qiao, Renping, Lesigang, Johannes, Dong, Gang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875647/
https://ncbi.nlm.nih.gov/pubmed/24778935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/worm.25214
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