Knockdown of Hsc70-5/mortalin Induces Loss of Synaptic Mitochondria in a Drosophila Parkinson’s Disease Model

Mortalin is an essential component of the molecular machinery that imports nuclear-encoded proteins into mitochondria, assists in their folding, and protects against damage upon accumulation of dysfunctional, unfolded proteins in aging mitochondria. Mortalin dysfunction associated with Parkinson’s d...

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Bibliografiske detaljer
Main Authors: Zhu, Jun-yi, Vereshchagina, Natalia, Sreekumar, Vrinda, Burbulla, Lena F., Costa, Ana C., Daub, Katharina J., Woitalla, Dirk, Martins, L. Miguel, Krüger, Rejko, Rasse, Tobias M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875477/
https://ncbi.nlm.nih.gov/pubmed/24386261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083714
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