Combination of Innate and Adaptive Immune Alterations Increased the Likelihood of Fibrostenosis in Crohn’s Disease

BACKGROUND: Mutations in the nucleotide oligomerization domain-2 (NOD2) gene and positive antibodies to microbial antigens have been found to be associated with the Crohn’s disease (CD) phenotype, fibrostenosis. The aim of this study was to confirm these relationships in a large cohort of CD patient...

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Autors principals: Ippoliti, Andrew, Devlin, Shane, Mei, Ling, Yang, Huiying, Papadakis, Konstantinos A., Vasiliauskas, Eric A., McGovern, Dermot P. B., Abreu, Maria T., Melmed, Gil, Shaye, Omid, Enayati, Pedram, Chen, Gary, Choi, Jennifer, Taylor, Kent, Landers, Carol J., Rotter, Jerome I., Targan, Stephan R.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875376/
https://ncbi.nlm.nih.gov/pubmed/20027650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.21196
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