Fluorescent Biphenyl Derivatives of Phenylalanine Suitable for Protein Modification

In a recent study, we demonstrated that structurally compact fluorophores incorporated into the side chains of amino acids could be introduced into dihydrofolate reductase from E. coli (ecDHFR) with minimal disruption of protein structure or function, even where the site of incorporation was within...

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Bibliografiske detaljer
Main Authors: Chen, Shengxi, Fahmi, Nour Eddine, Bhattacharya, Chandrabali, Wang, Lin, Jin, Yuguang, Benkovic, Stephen J., Hecht, Sidney M.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875372/
https://ncbi.nlm.nih.gov/pubmed/24152169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi401275v
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