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Fluorescent Biphenyl Derivatives of Phenylalanine Suitable for Protein Modification

In a recent study, we demonstrated that structurally compact fluorophores incorporated into the side chains of amino acids could be introduced into dihydrofolate reductase from E. coli (ecDHFR) with minimal disruption of protein structure or function, even where the site of incorporation was within...

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Detalhes bibliográficos
Main Authors: Chen, Shengxi, Fahmi, Nour Eddine, Bhattacharya, Chandrabali, Wang, Lin, Jin, Yuguang, Benkovic, Stephen J., Hecht, Sidney M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875372/
https://ncbi.nlm.nih.gov/pubmed/24152169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi401275v
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