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The N-terminal Zinc Finger and Flanking Basic Domains Represent the Minimal Region of HIV-1 Nucleocapsid Protein for Targeting Chaperone Function
The human immunodeficiency virus type-1 (HIV-1) nucleocapsid (NC) protein is a chaperone that facilitates nucleic acid conformational changes to form the most thermodynamically stable arrangement. The critical role of NC in many steps of the viral life cycle makes it an attractive therapeutic target...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3875364/ https://ncbi.nlm.nih.gov/pubmed/24144434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi401250a |
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