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Effect of Mg(2+) and Na(+) on the Nucleic Acid Chaperone Activity of HIV-1 Nucleocapsid Protein: Implications for Reverse Transcription

The human immunodeficiency virus type 1 (HIV-1) nucleocapsid protein (NC) is an essential protein for retroviral replication. Among its numerous functions, NC is a nucleic acid (NA) chaperone protein that catalyzes NA rearrangements leading to the formation of thermodynamically more stable conformat...

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Detalles Bibliográficos
Main Authors: My-Nuong, Vo, Barany, George, Rouzina, Ioulia, Musier-Forsyth, Karin
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2642912/
https://ncbi.nlm.nih.gov/pubmed/19154740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.12.073
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