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The N-terminal Zinc Finger and Flanking Basic Domains Represent the Minimal Region of HIV-1 Nucleocapsid Protein for Targeting Chaperone Function

The human immunodeficiency virus type-1 (HIV-1) nucleocapsid (NC) protein is a chaperone that facilitates nucleic acid conformational changes to form the most thermodynamically stable arrangement. The critical role of NC in many steps of the viral life cycle makes it an attractive therapeutic target...

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Detalhes bibliográficos
Main Authors: Mitra, Mithun, Wang, Wei, Vo, My-Nuong, Rouzina, Ioulia, Barany, George, Musier-Forsyth, Karin
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875364/
https://ncbi.nlm.nih.gov/pubmed/24144434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi401250a
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