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Identification of Hematopoietic Stem Cell Engraftment Genes in Gene Therapy Studies

Hematopoietic stem cell (HSC) therapy using replication-incompetent retroviral vectors is a promising approach to provide life-long correction for genetic defects. HSC gene therapy clinical studies have resulted in functional cures for several diseases, but in some studies clonal expansion or leukem...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Powers, John M, Trobridge, Grant D
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875223/
https://ncbi.nlm.nih.gov/pubmed/24383045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2157-7633.S3-004
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