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Large Animal Models of Hematopoietic Stem Cell Gene Therapy

Large animal models have been instrumental in advancing hematopoietic stem cell (HSC) gene therapy. Here we review the advantages of large animal models, their contributions to the field of HSC gene therapy, and recent progress in this field. Several properties of human HSCs including their purifica...

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Détails bibliographiques
Auteurs principaux: Trobridge, Grant D., Kiem, Hans-Peter
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914814/
https://ncbi.nlm.nih.gov/pubmed/20428209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2010.47
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