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Thyroid Hormone-Induced Hypertrophy in Mesenchymal Stem Cell Chondrogenesis Is Mediated by Bone Morphogenetic Protein-4

Chondrogenic differentiating mesenchymal stem cells (MSCs) express markers of hypertrophic growth plate chondrocytes. As hypertrophic cartilage undergoes ossification, this is a concern for the application of MSCs in articular cartilage tissue engineering. To identify mechanisms that elicit this phe...

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Autori principali: Karl, Alexandra, Olbrich, Norman, Pfeifer, Christian, Berner, Arne, Zellner, Johannes, Kujat, Richard, Angele, Peter, Nerlich, Michael, Mueller, Michael B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875213/
https://ncbi.nlm.nih.gov/pubmed/23937304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2013.0023
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