Insulin is essential for in vitro chondrogenesis of mesenchymal progenitor cells and influences chondrogenesis in a dose-dependent manner

PURPOSE: Insulin is a commonly used additive in chondrogenic media for differentiating mesenchymal stem cells (MSCs). The indispensability of other bioactive factors like TGF-β or dexamethasone in these medium formulations has been shown, but the role of insulin is unclear. The purpose of this study...

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Detalhes bibliográficos
Main Authors: Mueller, Michael B., Blunk, Torsten, Appel, Bernhard, Maschke, Angelika, Goepferich, Achim, Zellner, Johannes, Englert, Carsten, Prantl, Lukas, Kujat, Richard, Nerlich, Michael, Angele, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2012
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532630/
https://ncbi.nlm.nih.gov/pubmed/23229799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00264-012-1726-z
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