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Unfolding the Bridge between Transcription and Translation

Transcription antiterminator RfaH alternates between closed (inactive) and open (activated) conformation. In this issue of Cell, Burmann et al. show that opening is accompanied by dramatic all-α to all-β refolding of its C-terminal domain. Each of the folds has a distinct function: all-α-fold acts a...

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Autors principals: Svetlov, Vladimir, Nudler, Evgeny
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874879/
https://ncbi.nlm.nih.gov/pubmed/22817886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.06.025
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