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Unfolding the Bridge between Transcription and Translation
Transcription antiterminator RfaH alternates between closed (inactive) and open (activated) conformation. In this issue of Cell, Burmann et al. show that opening is accompanied by dramatic all-α to all-β refolding of its C-terminal domain. Each of the folds has a distinct function: all-α-fold acts a...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3874879/ https://ncbi.nlm.nih.gov/pubmed/22817886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.06.025 |
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