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Unfolding the Bridge between Transcription and Translation

Transcription antiterminator RfaH alternates between closed (inactive) and open (activated) conformation. In this issue of Cell, Burmann et al. show that opening is accompanied by dramatic all-α to all-β refolding of its C-terminal domain. Each of the folds has a distinct function: all-α-fold acts a...

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Detalles Bibliográficos
Main Authors: Svetlov, Vladimir, Nudler, Evgeny
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874879/
https://ncbi.nlm.nih.gov/pubmed/22817886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.06.025
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