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Enantio- and Regioselective CuH-Catalyzed Hydroamination of Alkenes

A highly enantio- and regioselective copper-catalyzed hydroamination reaction of alkenes has been developed using diethoxy(methyl)silane (DEMS) and esters of hydroxylamines. The process tolerates a wide variety of substituted styrenes, including trans-, cis-, and β,β-disubstituted styrenes to yield...

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Autores principales: Zhu, Shaolin, Niljianskul, Nootaree, Buchwald, Stephen L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874865/
https://ncbi.nlm.nih.gov/pubmed/24106781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4092819
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