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Cytidine derivatives as IspF inhibitors of Burkolderia pseudomallei

Published biological data suggest that the methyl erythritol phosphate (MEP) pathway, a non-mevalonate isoprenoid biosynthetic pathway, is essential for certain bacteria and other infectious disease organisms. One highly conserved enzyme in the MEP pathway is 2C-methyl-D-erythritol 2,4-cyclodiphosph...

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Detalhes bibliográficos
Main Authors: Zhang, Zheng, Jakkaraju, Sriram, Blain, Joy, Gogol, Kenneth, Zhao, Lei, Hartley, Robert C., Karlsson, Courtney A., Staker, Bart L., Stewart, Lance J., Myler, Peter J., Clare, Michael, Begley, Darren W., Horn, James R., Hagen, Timothy J
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874807/
https://ncbi.nlm.nih.gov/pubmed/24157367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.09.101
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