Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei

As part of the Seattle Structural Genomics Center for Infectious Disease, we seek to enhance structural genomics with ligand-bound structure data which can serve as a blueprint for structure-based drug design. We have adapted fragment-based screening methods to our structural genomics pipeline to ge...

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Detalhes bibliográficos
Main Authors: Begley, Darren W., Hartley, Robert C., Davies, Douglas R., Edwards, Thomas E., Leonard, Jess T., Abendroth, Jan, Burris, Courtney A., Bhandari, Janhavi, Myler, Peter J., Staker, Bart L., Stewart, Lance J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123455/
https://ncbi.nlm.nih.gov/pubmed/21359640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10969-011-9102-6
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