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S-adenosylmethionine limitation induces p38 mitogen-activated protein kinase and triggers cell cycle arrest in G1

The primary methyl group donor S-adenosylmethionine (SAM) is important for a plethora of cellular pathways including methylation of nucleic acids, proteins, and the 5′ cap structure of mRNAs, as well as biosynthesis of phospholipids and polyamines. In addition, because it is the cofactor for chromat...

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Autores principales: Lin, Da-Wei, Chung, Benjamin P., Kaiser, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874783/
https://ncbi.nlm.nih.gov/pubmed/24155332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.127811
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