Everolimus-induced human keratinocytes toxicity is mediated by STAT3 inhibition

BACKGROUND: Mammalian target of rapamycin (mTOR) inhibitors are associated with dermatological adverse events. The chief aim of this study was to examine the relation between the signal transducer and activator of transcription 3 (STAT3) protein and the dermatological adverse events associated with...

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Bibliografiske detaljer
Main Authors: Yamamoto, Kazuhiro, Uda, Atsushi, Mukai, Akira, Yamashita, Kazuhiko, Kume, Manabu, Makimoto, Hiroo, Bito, Toshinori, Nishigori, Chikako, Hirano, Takeshi, Hirai, Midori
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874739/
https://ncbi.nlm.nih.gov/pubmed/24423131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-32-83
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