Association of Toxicity of Sorafenib and Sunitinib for Human Keratinocytes with Inhibition of Signal Transduction and Activator of Transcription 3 (STAT3)

Hand–foot skin reaction is a most common multi-kinase inhibitor-related adverse event. This study aimed to examine whether the toxicity of sorafenib and sunitinib for human keratinocytes was associated with inhibiting signal transduction and activator of transcription 3 (STAT3). We studied whether S...

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Detalhes bibliográficos
Main Authors: Yamamoto, Kazuhiro, Mizumoto, Atsushi, Nishimura, Kohji, Uda, Atsushi, Mukai, Akira, Yamashita, Kazuhiko, Kume, Manabu, Makimoto, Hiroo, Bito, Toshinori, Nishigori, Chikako, Nakagawa, Tsutomu, Hirano, Takeshi, Hirai, Midori
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094497/
https://ncbi.nlm.nih.gov/pubmed/25013907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102110
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