Everolimus-induced human keratinocytes toxicity is mediated by STAT3 inhibition

BACKGROUND: Mammalian target of rapamycin (mTOR) inhibitors are associated with dermatological adverse events. The chief aim of this study was to examine the relation between the signal transducer and activator of transcription 3 (STAT3) protein and the dermatological adverse events associated with...

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Detalhes bibliográficos
Main Authors: Yamamoto, Kazuhiro, Uda, Atsushi, Mukai, Akira, Yamashita, Kazuhiko, Kume, Manabu, Makimoto, Hiroo, Bito, Toshinori, Nishigori, Chikako, Hirano, Takeshi, Hirai, Midori
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874739/
https://ncbi.nlm.nih.gov/pubmed/24423131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-32-83
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