Analysis of in vitro insulin resistance models and their physiological relevance to in vivo diet-induced adipose insulin resistance

Diet-induced obesity predisposes individuals to insulin resistance, and adipose tissue has a major role in the disease. Insulin resistance can be induced in cultured adipocytes by a variety of treatments, but it is unknown what aspects of the in vivo responses are captured by these models. We use gl...

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Main Authors: Lo, Kinyui Alice, Labadorf, Adam, Kennedy, Norman J., Han, Myoung Sook, Yap, Yoon Sing, Matthews, Bryan, Xin, Xiaofeng, Sun, Lei, Davis, Roger J., Lodish, Harvey F., Fraenkel, Ernest
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874466/
https://ncbi.nlm.nih.gov/pubmed/24095730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.08.039
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