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Extensive changes in DNA methylation are associated with expression of mutant huntingtin
The earliest stages of Huntington disease are marked by changes in gene expression that are caused in an indirect and poorly understood manner by polyglutamine expansions in the huntingtin (HTT) protein. To explore the hypothesis that DNA methylation may be altered in cells expressing mutated HTT, w...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3568325/ https://ncbi.nlm.nih.gov/pubmed/23341638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221292110 |
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