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Elucidating microRNA regulatory networks using transcriptional, post-transcriptional and histone modification measurements

MicroRNAs (miRNAs) regulate diverse biological processes by repressing mRNAs, but their modest effects on direct targets, together with their participation in larger regulatory networks, make it challenging to delineate miRNA-mediated effects. Here, we describe an approach to characterizing miRNA-re...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Gosline, Sara J.C., Gurtan, Allan M., JnBaptiste, Courtney K., Bosson, Andrew, Milani, Pamela, Dalin, Simona, Matthews, Bryan J., Yap, Yoon S., Sharp, Phillip A., Fraenkel, Ernest
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831719/
https://ncbi.nlm.nih.gov/pubmed/26748710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.12.031
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