Biodistribution and Molecular Studies on Orally Administered Nanoparticle-AON Complexes Encapsulated with Alginate Aiming at Inducing Dystrophin Rescue in mdx Mice

We have previously demonstrated that intraperitoneal injections of 2′-O-methyl-phosphorothioate (2′OMePS) antisense oligoribonucleotides adsorbed onto a cationic core-shell nanoparticles (NPs), termed ZM2, provoke dystrophin restoration in the muscles of mdx mice. The aim of the present work was to...

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Bibliografski detalji
Glavni autori: Falzarano, Maria Sofia, Passarelli, Chiara, Bassi, Elena, Fabris, Marina, Perrone, Daniela, Sabatelli, Patrizia, Maraldi, Nadir M., Donà, Silvia, Selvatici, Rita, Bonaldo, Paolo, Sparnacci, Katia, Laus, Michele, Braghetta, Paola, Rimessi, Paola, Ferlini, Alessandra
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2013
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874323/
https://ncbi.nlm.nih.gov/pubmed/24392452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/527418
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