Biodistribution and Molecular Studies on Orally Administered Nanoparticle-AON Complexes Encapsulated with Alginate Aiming at Inducing Dystrophin Rescue in mdx Mice

We have previously demonstrated that intraperitoneal injections of 2′-O-methyl-phosphorothioate (2′OMePS) antisense oligoribonucleotides adsorbed onto a cationic core-shell nanoparticles (NPs), termed ZM2, provoke dystrophin restoration in the muscles of mdx mice. The aim of the present work was to...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Falzarano, Maria Sofia, Passarelli, Chiara, Bassi, Elena, Fabris, Marina, Perrone, Daniela, Sabatelli, Patrizia, Maraldi, Nadir M., Donà, Silvia, Selvatici, Rita, Bonaldo, Paolo, Sparnacci, Katia, Laus, Michele, Braghetta, Paola, Rimessi, Paola, Ferlini, Alessandra
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Hindawi Publishing Corporation 2013
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874323/
https://ncbi.nlm.nih.gov/pubmed/24392452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/527418
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