Cationic PMMA Nanoparticles Bind and Deliver Antisense Oligoribonucleotides Allowing Restoration of Dystrophin Expression in the mdx Mouse

For subsets of Duchenne muscular dystrophy (DMD) mutations, antisense oligoribonucleotide (AON)-mediated exon skipping has proven to be efficacious in restoring the expression of dystrophin protein. In the mdx murine model systemic delivery of AON, recognizing the splice donor of dystrophin exon 23,...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Rimessi, Paola, Sabatelli, Patrizia, Fabris, Marina, Braghetta, Paola, Bassi, Elena, Spitali, Pietro, Vattemi, Gaetano, Tomelleri, Giuliano, Mari, Lara, Perrone, Daniela, Medici, Alessandro, Neri, Marcella, Bovolenta, Matteo, Martoni, Elena, Maraldi, Nadir M., Gualandi, Francesca, Merlini, Luciano, Ballestri, Marco, Tondelli, Luisa, Sparnacci, Katia, Bonaldo, Paolo, Caputo, Antonella, Laus, Michele, Ferlini, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835127/
https://ncbi.nlm.nih.gov/pubmed/19240694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.8
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados